Dynamic organelle localization and cytoskeltal reorganization during preimplantation mouse embryo developent reveald by live imaging of genetically encoded fluorescent fusion protein.
Kiyonari, H., Kaneko, M., Abe, T., Shioi, G., Furuta, Y., Fujimori T.
genesis. 2019 Feb;57(2):e23277.

ROSA26 reporter mouse line and image analyses reveal distinct region-specific cell behaviors in the visceral endoderm.
Abe, T., Kutsuna, N., Kiyonari, H., Furuta, Y., Fujimori T.
Development. 2018 Nov 21;145(22).

Apical constriction in distal visceral endoderm cells initiates global, collective cell rearrangement in embryonic visceral endoderm to form anterior visceral endoderm.
Shioi, G., Hoshino, H., Abe, T., Kiyonari, H., Nakao, K., Meng, W., Furuta, Y., Fujimori, T., and Aizawa, S. (2017).
Developmental biology. 2017 Sep 1;429(1):20-30

Reporter mouse lines for fluorescence imaging.
Abe T, Fujimori T.
Dev Growth Differ. 2013 May;55(4):390-405.

Visualization of cell cycle in mouse embryos with Fucci2 reporter directed by Rosa26 promoter.
Abe T, Sakaue-Sawano A, Kiyonari H, Shioi G, Inoue K, Horiuchi T, Nakao K, Miyawaki A, Aizawa S, Fujimori T.
Development. 2013 Jan 1;140(1):237-46.

Establishment of conditional reporter mouse lines at ROSA26 locus for live cell imaging.
Abe T, Kiyonari H, Shioi G, Inoue K, Nakao K, Aizawa S, Fujimori T.
Genesis. 2011 Jul;49(7):579-90.

A mouse reporter line to conditionally mark nuclei and cell membranes for in vivo live-imaging.
Shioi G, Kiyonari H, Abe T, Nakao K, Fujimori T, Jang CW, Huang CC, Akiyama H, Behringer RR, Aizawa S.
Genesis. 2011 Jul;49(7):570-8.

Kiyonari H, Kaneko M, Abe S, Aizawa S.
Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability. Genesis.2011 May;48(5):317-27.

Joint Developments：共同開発したマウスを使った論文

2017

Satake T, Yamashita K, Hayashi K, Miyatake S, Tamura-Nakano M, Doi H, Furuta Y, Shioi G, Miura E, Takeo YH, Yoshida K, Yahikozawa H, Matsumoto N, Yuzaki M, Suzuki A. (2017) MTCL1 plays an essential role in maintaining Purkinje neuron axon initial segment. EMBO J. pii: e201695630. doi: 10.15252/embj.201695630.

Kawakami K, Takeshita A, Furushima K, Miyajima M, Hatamura I, Kuro-O M, Furuta Y, Sakaguchi K. (2017) Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease. Sci Rep. 7:40534. doi: 10.1038/srep40534.

2016

Nakao H, Harada T, Nakao K, Kiyonari H, Inoue K, Furuta Y, Aiba A. (2016) A possible aid in targeted insertion of large DNA elements by CRISPR/Cas in mouse zygotes. Genesis. 54(2):65-77.

Shi D, Usami F, Komatsu K, Oka S, Abe T, Uemura T, Fujimori T. (2016) Dynamics of planar cell polarity protein Vangl2 in the mouse oviduct epithelium. Mech Dev. 141:78-89.
Ibeh BO, Furuta Y, Habu JB, Ogbadu L. (2016) Humanized mouse as an appropriate model for accelerated global HIV research and vaccine development: current trend. Immunopharmacol Immunotoxicol. 1-13.

Toya, M., Kobayashi, S., Kawasaki, M., Shioi, G., Kaneko, M., Ishiuchi, T., Misaki, K., Meng,.W, and Takeichi, M. (2016) CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells. Proc Natl Acad Sci U S A. 113(2):332-7.

Mukai, H., Muramatsu, A., Mashud, R., Kubouchi, K., Tsujimoto, S., Hongu, T., Kanaho, Y., Tsubaki, M., Nishida, S., Shioi, G., Danno, S., Mehruba, M., Satoh, R. and Sugiura, R. (2016) PKN3 is the major regulator of angiogenesis and tumor metastasis in mice. Sci Rep. 6:18979. doi: 10.1038/srep18979.

Watanabe S, Shioi G, Furuta Y, Goshima G. (2016) Intra-spindle Microtubule Assembly Regulates Clustering of Microtubule-Organizing Centers during Early Mouse Development. Cell Rep. 15(1):54-60.

Isozaki T, Komenoi S, Lu Q, Usuki T, Tomokata S, Matsutomo D, Sakai H, Bando K, Kiyonari H, Sakane F. (2016) Deficiency of diacylglycerol kinase η induces lithium-sensitive mania-like behavior. J Neurochem.138(3), 448-456.

Ip JY, Sone M, Nashiki C, Pan Q, Kitaichi K, Yanaka K, Abe T, Takao K, Miyakawa T, Blencowe BJ, Nakagawa S. (2016) Gomafu lncRNA knockout mice exhibit mild hyperactivity with enhanced responsiveness to the psychostimulant methamphetamine. Sci Rep. 6:27204. doi: 10.1038/srep27204.

Hata E, Sasaki N, Takeda A, Tohya K, Umemoto E, Akahoshi N, Ishii S, Bando K, Abe T, Kano K, Aoki J, Hayasaka H, Miyasaka M. (2016) Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes. Int Immunol. 28(6):283-92.

Haraguchi R, Kitazawa R, Mori K, Tachibana R, Kiyonari H, Imai Y, Abe T, Kitazawa S. sFRP4-dependent Wnt signal modulation is critical for bone remodeling during postnatal development and age-related bone loss. Sci Rep. 2016 Apr 27;6:25198. doi: 10.1038/srep25198.

Tokumasu R, Yamaga K, Yamazaki Y, Murota H, Suzuki K, Tamura A, Bando K, Furuta Y, Katayama I, Tsukita S. (2016) Dose-dependent role of claudin-1 in vivo in orchestrating features of atopic dermatitis. Proc Natl Acad Sci U S A. 113(28):E4061-8. doi: 10.1073/pnas.1525474113.

Hata K, Yanase N, Sudo K, Kiyonari H, Mukumoto Y, Mizuguchi J, Yokosuka T. (2016) Differential regulation of T-cell dependent and T-cell independent antibody responses through arginine methyltransferase PRMT1 in vivo. FEBS Lett. 590(8):1200-10. doi: 10.1002/1873-3468.12161.

Doi M, Murai I, Kunisue S, Setsu G, Uchio N, Tanaka R, Kobayashi S, Shimatani H, Hayashi H, Chao HW, Nakagawa Y, Takahashi Y, Hotta Y, Yasunaga J, Matsuoka M, Hastings MH, Kiyonari H, Okamura H. (2016) Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour. Nat Commun. 7:10583. doi: 10.1038/ncomms10583.

Nishi K, Sato Y, Ohno M, Hiraoka Y, Saijo S, Sakamoto J, Chen PM, Morita Y, Matsuda S, Iwasaki K, Sugizaki K, Harada N, Mukumoto Y, Kiyonari H, Furuyama K, Kawaguchi Y, Uemoto S, Kita T, Inagaki N, Kimura T, Nishi E. (2016) Nardilysin Is Required for Maintaining Pancreatic β-Cell Function. Diabetes. 65(10):3015-27.

Connor SA, Ammendrup-Johnsen I, Chan AW, Kishimoto Y, Murayama C, Kurihara N, Tada A, Ge Y, Lu H, Yan R, LeDue JM, Matsumoto H, Kiyonari H, Kirino Y, Matsuzaki F, Suzuki T, Murphy TH, Wang YT, Yamamoto T, Craig AM. (2016) Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2. Neuron. 91(5):1052-68.

Usuki T, Takato T, Lu Q, Sakai H, Bando K, Kiyonari H, Sakane, F. (2016) Behavioral and pharmacological phenotypes of brain-specific diacylglycerol kinase δ-knockout mice. Brain Res. 1648 (Part A), 193–201.

Makihara H, Nakai S, Ohkubo W, Yamashita N, Nakamura F, Kiyonari H, Shioi G, Jitsuki-Takahashi A, Nakamura H, Tanaka F, Akase T, Kolattukudy P, Goshima Y. (2016) CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development. Genes Cells. 21(9):994-1005.

Miyake K, Ohta T, Nakayama H, Doe N, Terao Y, Oiki E, Nagatomo I, Yamashita Y, Abe T, Nishikura K, Kumanogoh A, Hashimoto K, Kawahara Y. (2016) CAPS1 RNA Editing Promotes Dense Core Vesicle Exocytosis. Cell Reports 17(8): 2004-2014.

Higuchi M, Kawamura H, Matsuki H, Hara T, Takahashi M, Saito S, Saito K, Jiang S, Naito M, Kiyonari H, Fujii M. (2016) USP10 Is an Essential Deubiquitinase for Hematopoiesis and Inhibits Apoptosis of Long-Term Hematopoietic Stem Cells. Stem Cell Reports. 7(6):1116-1129.

Kusano R, Fujita K, Shinoda Y, Nagaura Y, Kiyonari H, Abe T, Watanabe T, Matsui Y, Fukaya M, Sakagami H, Sato T, Funahashi JI, Ohnishi M, Tamura S, Kobayashi T. (2016) Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 590(20):3606-3615.